Search results for "Opioids"
MKSAP Quiz: Evaluation for confusion
A 63-year-old man is evaluated in the ED for confusion. He recently visited an urgent care center for symptoms of an upper respiratory tract infection and was prescribed codeine-guaifenesin. Following a physical exam and administration of naloxone, what is the most likely cause of this patient's adverse drug reaction?
https://immattersacp.org/weekly/archives/2022/12/06/4.htm
6 Dec 2022
MKSAP Quiz: Evaluation for low back pain
A 47-year-old man is evaluated for low back pain. The pain began 5 days ago while he was playing basketball. It is localized to the lumbar back and does not radiate. The patient is unable to sit or stand for long periods, but the pain improves when lying down. After a physical exam, what is the most appropriate next step in management?
https://immattersacp.org/weekly/archives/2022/05/17/4.htm
17 May 2022
Treatment pathways compared for diabetic peripheral neuropathy
Amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin were similarly effective for controlling pain, a recent study found.
https://immattersacp.org/weekly/archives/2022/08/30/2.htm
30 Aug 2022
Some serious risks of long-term opioid therapy may be dose-dependent
Long-term opioid therapy is associated with increased risk for serious harms such as overdose, opioid abuse, fractures, and myocardial infarction, and some of the effect may be dose-dependent, according to a systematic review.
https://immattersacp.org/weekly/archives/2015/01/13/1.htm
13 Jan 2015
Mixing alcohol with opioids, benzodiazepines sending users to emergency departments
Nearly one-fifth of opioid abuse-related ED visits and more than one-fourth of benzodiazepine abuse-related ED visits involved alcohol, a study found.
https://immattersacp.org/weekly/archives/2014/10/21/1.htm
21 Oct 2014
Extended-release morphine didn't improve breathlessness in COPD
Patients with chronic obstructive pulmonary disease (COPD) randomized to two different doses of morphine or placebo for three weeks reported similar effects on breathlessness, an Australian trial found. Their step count also didn't change.
https://immattersacp.org/weekly/archives/2022/11/29/1.htm
29 Nov 2022
Neurologists suggest steps for prescribing opioids for chronic pain
The American Academy of Neurology issued a position paper outlining steps that can help physicians who prescribe chronic opioid analgesic therapy (COAT) for chronic noncancer pain (CNCP).
https://immattersacp.org/weekly/archives/2014/10/07/1.htm
7 Oct 2014
Few high-quality guidelines exist for prescribing opioids
Few high-quality guidelines exist for prescribing opioids to treat chronic pain, a review found, noting that there was at least consensus among guidelines on ways to mitigate opioid-related risks.
https://immattersacp.org/weekly/archives/2013/11/12/1.htm
12 Nov 2013
‘Considerable uncertainty’ surrounds efficacy, safety of analgesics for low back pain
A systematic review and meta-analysis of 98 randomized controlled trials found little high-certainty evidence on the comparative effectiveness and safety of analgesics for acute nonspecific low back pain.
https://immattersacp.org/weekly/archives/2023/03/28/1.htm
28 Mar 2023
Nonopioids effective for acute low back pain, review finds
Myorelaxants and NSAIDs with or without acetaminophen were all effective at reducing pain and disability from acute, nonspecific low back pain lasting less than 12 weeks, according to an analysis of 18 randomized controlled trials, although the authors stressed that medications for this condition should always be a second-line strategy.
https://immattersacp.org/weekly/archives/2023/02/28/1.htm
28 Feb 2023