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Atypical femur fracture risk increases with longer bisphosphonate use, drops after discontinuation

Researchers studied women ages 50 years or older who took bisphosphonates and were enrolled in the Kaiser Permanente Southern California health care system.
https://immattersacp.org/weekly/archives/2020/08/25/3.htm
25 Aug 2020

Aspirin's use, effectiveness debated

This issue covers topics including aspirin's role in cardiovascular health, conference coverage for palliative care, and the growth of free clinics in medical education.
https://immattersacp.org/archives/2015/05/editors.htm
1 May 2015

MKSAP Quiz: Evaluation for a new-patient visit

A 55-year-old woman is evaluated for a new-patient visit. Medical history is significant for an eating disorder. Although she has maintained a normal weight for the past 20 years, she notes that prior to that time her weight would fluctuate in a range correlating with BMIs of 17 to 19. Family history is significant for postmenopausal osteoporosis in her mother. Following a physical exam and lab studies, what is the most appropriate management of this patient?
https://immattersacp.org/weekly/archives/2018/03/27/3.htm
27 Mar 2018

MKSAP Quiz: Hypothyroidism

A 70-year-old woman with hypothyroidism fell and fractured her hip. During preoperative evaluation for hip fracture repair, she mentions recent mild fatigue, which has not significantly limited performance of her daily activities, and ongoing right upper-quadrant abdominal pain after eating. Following a physical exam and lab results, what management option is most appropriate?.
https://immattersacp.org/archives/2010/04/mksap.htm
1 Apr 2010

Canagliflozin may not increase fracture risk in patients at low risk for fractures

Although canagliflozin has been linked to decreased bone mineral density, patients with type 2 diabetes who initiated the drug had similar risk of a first fracture as those who started a glucagon-like peptide-1 receptor agonist.
https://immattersacp.org/weekly/archives/2019/01/08/2.htm
8 Jan 2019

Survey finds some patients hate pills more than others

Physicians prescribing and talking to patients about medication should keep in mind their patients' disdain for taking pills and the lengths they will go to not have to take them.
https://immattersacp.org/archives/2015/05/pills.htm
1 May 2015

Menopausal hormone therapy linked to breast cancer risk

An individual patient-level meta-analysis found that risk for breast cancer increased steadily with duration of use for all types of menopausal hormone therapy except vaginal estrogen and that risk was higher with estrogen-progestogen than estrogen-only formulations.
https://immattersacp.org/weekly/archives/2019/09/10/1.htm
10 Sep 2019

Warnings on fluoroquinolones, antipsychotics, becaplermin

Recalls, warnings, and approvals.
https://immattersacp.org/archives/2008/09/fda.htm
1 Sep 2008

MKSAP Quiz: Evaluation for primary hyperparathyroidism

A 67-year-old man is evaluated for a recent diagnosis of primary hyperparathyroidism after an elevated serum calcium level was incidentally detected on laboratory testing. Medical history is significant only for hypertension, and his only medication is ramipril. Following a physical exam and lab studies, what is the most appropriate management of this patient?
https://immattersacp.org/weekly/archives/2017/02/14/3.htm
14 Feb 2017

Get rid of GERD without unneeded costs, tests

Gastroesophageal reflux disease can be diagnosed in the office, without the need for expensive tests such as endoscopy. Learn how to make the right diagnosis while avoiding confounding symptoms that might steer a patient toward the wrong specialist.
https://immattersacp.org/archives/2014/06/GERD.htm
1 Jun 2014

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