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MKSAP Quiz: ED visit for progressive weakness

A 64-year-old man is evaluated in the emergency department for progressive weakness. He recently attended a national conference where three colleagues developed similar symptoms. Following a physical exam, lab and other studies, and imaging, what is the most likely diagnosis?
https://immattersacp.org/weekly/archives/2025/05/13/3.htm
13 May 2025

MKSAP Quiz: Follow-up evaluation for thrombocytopenia

A 35-year-old patient presents for follow-up evaluation for thrombocytopenia. Peripheral blood smear shows normochromic, normocytic erythrocytes and normal leukocytes; occasional large platelets are noted. Following a physical exam and lab studies, what is the most appropriate management?
https://immattersacp.org/weekly/archives/2025/05/06/3.htm
6 May 2025

MKSAP Quiz: Evaluation in the ED for rash

A 42-year-old patient is evaluated in the emergency department for a rash. Four days ago, they developed fever, malaise, and a headache; these symptoms resolved after 2 to 3 days and were followed by the rash, which started as small erythematous macules that developed into papules. Following a physical exam, what is the most likely diagnosis?
https://immattersacp.org/archives/2025/05/mksap-quiz-evaluation-in-the-ed-for-rash.htm
1 May 2025

MKSAP Quiz: 3-week history of fever, dyspnea on exertion

A 41-year-old woman is evaluated for a 3-week history of fever, dyspnea on exertion, and dry cough. These symptoms have persisted despite an initial empiric course of amoxicillin; additionally, levofloxacin was initiated 4 days ago without improvement. Following a physical exam and other tests, what is the most appropriate diagnostic test to perform next?
https://immattersacp.org/weekly/archives/2025/04/29/3.htm
29 Apr 2025

MKSAP Quiz: Abdominal distention in cirrhosis

A 65-year-old man is evaluated in the ED for abdominal distention. He reports increasing discomfort and abdominal girth of 2 weeks' duration. Following a physical exam and lab studies, what is the most appropriate treatment before paracentesis?
https://immattersacp.org/weekly/archives/2025/04/22/3.htm
22 Apr 2025

MKSAP Quiz: 3-month history of symmetric polyarthritis

A 72-year-old patient is evaluated for a 3-month history of symmetric polyarthritis of the wrists and metacarpophalangeal joints. Two previous episodes of acute knee swelling self-resolved within 2 weeks. Following a physical exam, lab studies, and other tests, what is the most appropriate treatment?
https://immattersacp.org/weekly/archives/2025/04/15/3.htm
15 Apr 2025

MKSAP Quiz: 2-week history of dysphagia

A 70-year-old woman is hospitalized for a 2-week history of dysphagia to solids and odynophagia. She has locally advanced non–small cell lung cancer and is undergoing chemotherapy. Following a physical exam and other procedures, what is the most appropriate treatment?
https://immattersacp.org/archives/2025/04/mksap-quiz-2-week-history-of-dysphagia.htm
1 Apr 2025

MKSAP Quiz: 1-week history of gross hematuria

A 65-year-old man is evaluated for a 1-week history of gross hematuria. Medical history is otherwise unremarkable. After a physical exam and lab studies, what is the most appropriate diagnostic test?
https://immattersacp.org/weekly/archives/2025/03/25/3.htm
25 Mar 2025

MKSAP Quiz: Headaches, fever, painful rash

A 27-year-old man is evaluated in the emergency department for a 1-week history of headaches, fever, cough, painful rash, and swollen painful lymph nodes. He recently had unprotected receptive anal intercourse with a new male partner. Medical history is significant for HIV infection. Following a physical exam and lab studies, which of the following viruses is the most likely diagnosis?
https://immattersacp.org/weekly/archives/2025/03/18/3.htm
18 Mar 2025

MKSAP Quiz: Progressive head tremor

A 61-year-old man is evaluated for a head tremor that started 5 years ago and has slowly progressed. He notes that people often ask him if he is agreeing with them. Following a physical exam and lab studies, what is the most appropriate treatment?
https://immattersacp.org/weekly/archives/2025/03/11/3.htm
11 Mar 2025

MKSAP Quiz: Evaluation in the ED for hematemesis

A 39-year-old man is evaluated in the emergency department for hematemesis. He has a history of alcoholic cirrhosis and was diagnosed with hepatic encephalopathy 1 month ago. Following a physical exam and lab studies, what is the most appropriate treatment?
https://immattersacp.org/weekly/archives/2025/03/04/3.htm
4 Mar 2025

MKSAP Quiz: Evaluation in the emergency department after chest discomfort

A 54-year-old woman is evaluated in the emergency department 3 hours after a 30-minute episode of chest discomfort. She is currently pain free. She reports a 2-day history of recurrent episodes of chest “fullness” while at rest. Following a physical exam and other tests, what is the most appropriate diagnostic test to perform next?
https://immattersacp.org/archives/2025/03/mksap-quiz-evaluation-in-the-emergency-department-after-chest-discomfort.htm
1 Mar 2025

MKSAP Quiz: Evaluation for episodes of headaches

A 25-year-old patient is evaluated for episodes of headache that have become more frequent over the past three years, which the patient attributes to increased stress after starting graduate school. Following a physical exam and other findings, what is the most likely diagnosis?
https://immattersacp.org/weekly/archives/2025/02/25/3.htm
25 Feb 2025

MKSAP Quiz: Left leg swelling after surgery

A 42-year-old woman is evaluated in the hospital for swelling of the left leg 2 days after undergoing resection of a glioblastoma multiforme. She reports a mild headache and left-sided weakness. Following resection, a physical exam, and other procedures, what is the most appropriate management?
https://immattersacp.org/weekly/archives/2025/02/18/3.htm
18 Feb 2025

MKSAP Quiz: Medication after STEMI

A 69-year-old man is evaluated in the hospital 3 days after presenting with chest pain due to an acute inferior wall ST-elevation myocardial infarction (STEMI). He underwent urgent coronary angiography and successful drug-eluting stent placement. What is the most appropriate antithrombotic treatment strategy?
https://immattersacp.org/weekly/archives/2025/02/11/3.htm
11 Feb 2025

MKSAP Quiz: 3-week history of repeated coughing

A 35-year-old woman is evaluated for a 3-week history of repeated paroxysms of sustained coughing accompanied by vomiting. She has tried over-the-counter cough suppressants with minimal benefit. One week before onset of her current symptoms, she experienced 3 to 4 days of mild upper airway congestion and malaise, which resolved without treatment. Following a physical exam, what is the most appropriate management?
https://immattersacp.org/weekly/archives/2025/02/04/3.htm
4 Feb 2025

MKSAP Quiz: Progressive shortness of breath, dry cough

A 67-year-old man is evaluated for progressive shortness of breath and dry cough over the past 3 months. He has a 40-pack-year history of cigarette smoking. His only medication is an albuterol inhaler. Following a physical exam and other tests, what is the most likely diagnosis?
https://immattersacp.org/archives/2025/02/mksap-quiz-progressive-shortness-of-breath-dry-cough.htm
1 Feb 2025

MKSAP Quiz: Follow-up for osteoporosis

A 66-year-old woman is evaluated in follow-up for osteoporosis. The patient is concerned because alendronate resulted in upper gastrointestinal symptoms and IV zoledronic acid 1 year ago led to mild body aches, nausea, and headache. What is the most appropriate management?
https://immattersacp.org/weekly/archives/2025/01/28/3.htm
28 Jan 2025

MKSAP Quiz: Evaluation for exertional dyspnea

A 35-year-old man is evaluated for exertional dyspnea. His history is otherwise unremarkable. Following a physical exam and other testing, what is the most appropriate management?
https://immattersacp.org/weekly/archives/2025/01/21/3.htm
21 Jan 2025

MKSAP Quiz: Discussing results of bone mineral density testing

A 46-year-old woman is evaluated at a follow-up visit to discuss results of bone mineral density testing. She has a 10-year history of myasthenia gravis and is receiving long-term glucocorticoid therapy. Following a fracture risk assessment, what is the most appropriate treatment?
https://immattersacp.org/weekly/archives/2025/01/14/3.htm
14 Jan 2025

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