Search results for "Gout"
Urate-lowering therapy associated with benefit in patients with gout and CKD
The five-year risk of severe or end-stage chronic kidney disease (CKD) was lower in patients with CKD and gout who achieved a target serum urate level of less than 6 mg/dL compared to those who did not, data from the United Kingdom show.
https://immattersacp.org/weekly/archives/2024/12/03/4.htm
3 Dec 2024
Serum urate level may predict flare risk in patients with gout
Approximately 95% of acute gout episodes requiring treatment occurred in patients who had a serum urate level of at least 6 mg/dL at baseline while 98% occurred in those with a baseline level of at least 5 mg/dL, according to a study using UK Biobank data on 1,773 episodes over a mean follow-up of 8.3 years.
https://immattersacp.org/weekly/archives/2024/02/13/1.htm
13 Feb 2024
Allopurinol not associated with increased mortality in patients with CKD, gout
The findings of a database analysis from the United Kingdom provide reassurance that a treat-to-target strategy has no apparent harmful effect on mortality in patients with gout and chronic kidney disease (CKD).
https://immattersacp.org/weekly/archives/2022/01/25/2.htm
25 Jan 2022
Guideline recommends allopurinol as first-line therapy for gout
The American College of Rheumatology noted that the drug is the preferred choice for urate-lowering therapy in all patients, including those with moderate to severe chronic kidney disease.
https://immattersacp.org/weekly/archives/2020/05/19/4.htm
19 May 2020
Studies analyze causes of hyperuricemia, kidney effects of gout treatment with allopurinol
Genetics contribute more than diet to hyperuricemia in healthy people, and 300 mg of allopurinol per day was associated with lower risk of chronic kidney disease in people with gout, recent research found.
https://immattersacp.org/weekly/archives/2018/10/16/1.htm
16 Oct 2018
Cardiovascular safety of febuxostat and allopurinol compared in patients with gout and CVD
In a modified intention-to-treat analysis, the primary end point of first occurrence of cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or urgent revascularization for unstable angina occurred in 10.8% of patients taking febuxostat and in 10.4% of patients taking allopurinol (hazard ratio, 1.03).
https://immattersacp.org/weekly/archives/2018/03/20/4.htm
20 Mar 2018
Clinical practice guideline for acute gout recommends corticosteroids, NSAIDs, low-dose colchicine
For diagnosis, a separate guideline recommended that physicians use synovial fluid analysis when clinical judgment indicates that diagnostic testing is necessary in patients with possible gout.
https://immattersacp.org/weekly/archives/2016/11/01/1.htm
1 Nov 2016
Corticosteroids may be viable first-line alternative to NSAIDs for acute gout
The study provides evidence that oral corticosteroids are as effective at treating pain and as acceptable to patients as non-steroidal anti-inflammatory drugs, and that they should be considered as a first-line alternative in the treatment of patients with acute gout.
https://immattersacp.org/weekly/archives/2016/02/23/4.htm
23 Feb 2016
Nighttime gout attack risk may be twice as much as in daytime
The risk of acute gout attacks was more than twice as high during the night or early morning hours than the day, even among those who did not consume alcohol and had a low purine intake during the 24 hours prior to the attack, a study found.
https://immattersacp.org/weekly/archives/2014/12/16/5.htm
16 Dec 2014
Pegloticase effective in treatment refractory patients
The drug pegloticase successfully treated gout in patients who had been refractory to conventional treatment.
https://immattersacp.org/weekly/archives/2011/08/23/5.htm
23 Aug 2011